Scotland flanker Hamish Watson has been ruled out of the rest of the Rugby World Cup because of a knee injury suffered in Sunday's defeat by Ireland.
The 27-year-old back-row will be replaced in the squad by Edinburgh club-mate Magnus Bradbury.
Watson fell awkwardly after being cleared from a ruck and left the field on a stretcher just before half-time.
Scotland head coach Gregor Townsend said: "We feel for Hamish, who had worked so hard for this opportunity."
A scan after the game confirmed the damage to the knee was significant enough to mean Watson will play no further part in the tournament.
"While there is a high probability of picking up injuries during a World Cup, it's always disappointing to see someone having to head home," Townsend added.
Bradbury is already in Japan, having travelled as precautionary injury cover for Jamie Ritchie, who missed the opening game with a facial injury suffered in the final warm-up match against Georgia.
Ritchie is expected to be fit to face Samoa in Scotland's second group game next Monday (11:15 BST).
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